GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1359733
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Trap1
Name: TNF receptor-associated protein 1
Acc ID: CHEBI:4356
Term: desferrioxamine B
Definition: An acyclic desferrioxamine that has formula C25H48N6O8.
Chemical ID: MESH:D003676
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:13468376480464CTDDeferoxamine results in decreased expression of TRAP1 mRNA

Deferoxamine results in decreased expression of TRAP1 protein

PMID:16927372
multiple interactionsISOCRRD:13468376480464CTDTRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]

PMID:16927372
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.