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GENE - TERM ANNOTATION REPORT

CRRD ID: 14114055
Species: Sus scrofa
CRRD Object: Gene
Symbol: RAB11A
Name: RAB11A, member RAS oncogene family
Acc ID: GO:0006887
Term: exocytosis
Definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
Definition Source(s): GOC:mah, ISBN:0716731363, PMID:22323285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0015790, MGI:MGI:99425, PANTHER:PTN000633981, RGD:68369, SGD:S000000833, SGD:S000003178, UniProtKB:P62491, UniProtKB:Q1590714298760GO_Central (PMID:21873635)

PMID:21873635
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.