Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 14139300
Species: Sus scrofa
CRRD Object: Gene
Symbol: MIR125A
Name: microRNA mir-125a
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR125Adecreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of MIR125A mRNA

PMID:26607349
MIR125Amultiple interactionsEXP 6480464CTD[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein, [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein, [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein, [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein, Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein], MIR125A mRNA inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein], MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein], MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein], MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein], MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein], Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein], Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein], Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein], Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein], Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]

PMID:26607349
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.