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CRRD ID: 14234910
Species: Sus scrofa
CRRD Object: Gene
Symbol: RAD51AP1
Name: RAD51 associated protein 1
Acc ID: GO:0036297
Term: interstrand cross-link repair
Definition: Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
Definition Source(s): GOC:vw, PMID:16464006, PMID:22064477
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RAD51AP1 IBAPANTHER:PTN001809412, UniProtKB:Q96B01, UniProtKB:Q9H1E314298760GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.