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GENE - TERM ANNOTATION REPORT

CRRD ID: 14259032
Species: Sus scrofa
CRRD Object: Gene
Symbol: CDC42EP4
Name: CDC42 effector protein 4
Acc ID: GO:0005856
Term: cytoskeleton
Definition: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Definition Source(s): GOC:mah, ISBN:0198547684, PMID:16959967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDC42EP4 IBAPANTHER:PTN001034302, UniProtKB:O14613, UniProtKB:Q9H3Q1, UniProtKB:Q9UKI214298760GO_Central (PMID:21873635)

PMID:21873635
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.