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GENE - TERM ANNOTATION REPORT

CRRD ID: 14264682
Species: Sus scrofa
CRRD Object: Gene
Symbol: WIPF3
Name: WAS/WASL interacting protein family member 3
Acc ID: GO:0005884
Term: actin filament
Definition: A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Definition Source(s): GOC:mah, ISBN:0198506732, PMID:10666339
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
WIPF3 IBAMGI:MGI:2178801, PANTHER:PTN001506182, RGD:620887, UniProtKB:P4276814298760GO_Central (PMID:21873635)

PMID:21873635
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.