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GENE - TERM ANNOTATION REPORT

CRRD ID: 14268113
Species: Sus scrofa
CRRD Object: Gene
Symbol: CHRNA4
Name: cholinergic receptor nicotinic alpha 4 subunit
Acc ID: DOID:0050742
Term: nicotine dependence
Definition: A substance dependence that is characterized by a physical dependence on nicotine. (DO)
Definition Source(s): url:https://en.wikipedia.org/wiki/Nicotine_dependence "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CHRNA4susceptibilityISORGD:103567240710OMIM  
CHRNA4 ISORGD:103569068941CTDCTD Direct Evidence: marker/mechanism

 
CHRNA4 ISORGD:86403499068941ClinVarClinVar Annotator: match by term: Nicotine addiction, protection against

PMID:15154117, PMID:25741868, PMID:26467025
CHRNA4 ISORGD:86403509068941ClinVarClinVar Annotator: match by term: Nicotine addiction, protection against

PMID:15154117, PMID:25741868, PMID:26467025
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.