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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1556985
Species: Mus musculus
CRRD Object: Gene
Symbol: Tgm3
Name: transglutaminase 3, E polypeptide
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of TGM3 mRNA

PMID:26377647
increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TGM3 mRNA

PMID:27562557
increases expressionISORGD:13434926480464CTDTetrachlorodibenzodioxin results in increased expression of TGM3 mRNA

PMID:16985168, PMID:21802500, PMID:23152189
multiple interactionsISORGD:13434926480464CTDresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TGM3 mRNA]

PMID:16985168
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.