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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1560955
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ndufa1
Name: NADH:ubiquinone oxidoreductase subunit A1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13504976480464CTDAcetaminophen results in decreased expression of NDUFA1 mRNA

PMID:25704631, PMID:29067470, PMID:31059760
multiple interactionsISORGD:13504976480464CTD[Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of NDUFA1 mRNA

PMID:31059760
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.