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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1561030
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Deptor
Name: DEP domain containing MTOR-interacting protein
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13442616480464CTDEstradiol results in increased expression of DEPDC6 mRNA, Estradiol results in increased expression of DEPTOR mRNA

PMID:19167446, PMID:19619570, PMID:23019147, PMID:25321415
multiple interactionsISORGD:13442616480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DEPTOR mRNA

PMID:19619570
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.