GENE - TERM ANNOTATION REPORT

CRRD ID: 1593265
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Atm
Name: ATM serine/threonine kinase
Acc ID: DOID:9007193
Term: Prolymphocytic Leukemia, T-Cell
Definition: A lymphoid leukemia characterized by a profound LYMPHOCYTOSIS with or without LYMPHADENOPATHY, hepatosplenomegaly, frequently rapid progression, and short survival. It was formerly called T-cell chronic lymphocytic leukemia.
Definition Source(s): MESH:D015461
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISOCRRD:16060408554872ClinVarClinVar Annotator: match by term: T-cell prolymphocytic leukemia

PMID:10817650, PMID:11382771, PMID:11805335, PMID:12195425, PMID:12552559, PMID:19431188, PMID:21787400, PMID:21792198, PMID:21933854, PMID:22649200, PMID:25741868, PMID:28492532, PMID:6504056, PMID:7792600, PMID:8797579, PMID:8808599, PMID:8845835, PMID:8923007, PMID:9150358, PMID:9288106, PMID:9443866, PMID:9463314
 ISOCRRD:16060408554872ClinVarClinVar Annotator: match by term: T-cell prolymphocytic leukemia, somatic

PMID:10534763, PMID:10607471, PMID:11382771, PMID:11830610, PMID:12205473, PMID:12810666, PMID:15880680, PMID:15928302, PMID:16958054, PMID:17001622, PMID:18575927, PMID:18634022, PMID:19348699, PMID:19431188, PMID:19781682, PMID:21787400, PMID:22529920, PMID:24088041, PMID:24733792, PMID:25741868, PMID:25980754, PMID:26506520, PMID:26633545, PMID:27528516, PMID:27595995, PMID:28492532, PMID:8755918, PMID:9288106, PMID:9463314
 ISOCRRD:16060408554872ClinVarClinVar Annotator: match by term: T-cell prolymphocytic leukemia, UMLS MESH term: T-Lymphocytic Leukemia, Chronic

PMID:9288106
 ISOCRRD:16060408554872ClinVarClinVar Annotator: match by term: T-cell prolymphocytic leukemia, UMLS MESH term: T-Lymphocytic Leukemia, Chronic

PMID:9334731
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.