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GENE - TERM ANNOTATION REPORT

CRRD ID: 1603444
Species: Homo sapiens
CRRD Object: Gene
Symbol: SLX1A
Name: SLX1 homolog A, structure-specific endonuclease subunit
Acc ID: GO:0000724
Term: double-strand break repair via homologous recombination
Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Definition Source(s): GOC:elh, PMID:10357855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAPANTHER:PTN000463591, UniProtKB:Q9BQ83, WB:WBGene000189092290271GO_Central (PMID:21873635)

PMID:21873635
 IMP 2290271UniProtKB (PMID:19595721)

PMID:19595721
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.