Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1603606
Species: Homo sapiens
CRRD Object: Gene
Symbol: ECRG4
Name: ECRG4 augurin precursor
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ECRG4affects expressionEXP 6480464CTDValproic Acid affects the expression of ECRG4 mRNA

PMID:25979313
ECRG4decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of ECRG4 mRNA

PMID:23179753
ECRG4increases expressionEXP 6480464CTDValproic Acid results in increased expression of ECRG4 mRNA

PMID:24935251, PMID:26272509, PMID:29154799
ECRG4multiple interactionsEXP 6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ECRG4 mRNA

PMID:27188386
ECRG4increases expressionISORGD:13056456480464CTDValproic Acid results in increased expression of ECRG4 mRNA

PMID:29427782
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.