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GENE - TERM ANNOTATION REPORT

CRRD ID: 1604786
Species: Homo sapiens
CRRD Object: Gene
Symbol: CEP290
Name: centrosomal protein 290
Acc ID: GO:0005813
Term: centrosome
Definition: A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
Definition Source(s): GOC:mah, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IDA 2290271HPA GO_REF:0000052, PMID:14654843, PMID:16682973, PMID:21399614, PMID:24550735
colocalizes_withIDA 2290271SYSCILIA_CCNET PMID:24648492
 IEAInterPro:IPR0262012290271InterPro GO_REF:0000002
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.