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CRRD ID: 1605896
Species: Homo sapiens
CRRD Object: Gene
Symbol: ISX
Name: intestine specific homeobox
Acc ID: GO:0000981
Term: DNA-binding transcription factor activity, RNA polymerase II-specific
Definition: A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
Definition Source(s): GOC:txnOH-2018
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0010323, FB:FBgn0011701, FB:FBgn0023489, MGI:MGI:108359, MGI:MGI:1097716, MGI:MGI:1918847, PANTHER:PTN002518769, UniProtKB:Q15699, UniProtKB:Q8N693, UniProtKB:Q96QS3, UniProtKB:Q99453, WB:WBGene000004402290271GO_Central (PMID:21873635)

 ISAtfclass:3.1.32290271NTNU_SB GO_REF:0000113
 ISMInterPro:IPR001356, InterPro:IPR0090572290271NTNU_SB (PMID:19274049)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.