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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1615939
Species: Mus musculus
CRRD Object: Gene
Symbol: Thbs1
Name: thrombospondin 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of THBS1 mRNA

PMID:15056808, PMID:25827057, PMID:27339419
multiple interactionsEXP 6480464CTD[Carbon Tetrachloride co-treated with 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea] results in increased expression of THBS1 mRNA, [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of THBS1 mRNA

PMID:25827057, PMID:30517762
increases expressionISORGD:15884556480464CTDCarbon Tetrachloride results in increased expression of THBS1 mRNA

PMID:31150632
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.