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GENE - TERM ANNOTATION REPORT

CRRD ID: 18908810
Species: Heterocephalus glaber
CRRD Object: Gene
Symbol: Kat2a
Name: lysine acetyltransferase 2A
Acc ID: PW:0001338
Term: histone modification pathway
Definition: The tails of histone proteins are subject to a wide array of modifications of which methylation and acetylation have been more thoroughly documented. The modified residues are recognized by particular proteins or readers, in turn acting upon their targets. The modifications are rendered reversible by the enzymes that carry out the reaction in the opposite direction, also referred to as erasers.
Definition Source(s): PMID:21655945, PMID:22203491, PMID:23085398
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.