GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2085
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:86228
Term: dithionitrobenzoic acid
Definition: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.
Chemical ID: MESH:D004228
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases reductionISOCRRD:7354046480464CTDALB protein results in increased reduction of Dithionitrobenzoic Acid

PMID:25451573
multiple interactionsISOCRRD:7354046480464CTD[ALB protein binds to Docosahexaenoic Acids] inhibits the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein binds to Eicosapentaenoic Acid] inhibits the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein binds to Myristic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein binds to Palmitic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein binds to stearic acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]

[ALB protein modified form binds to Myristic Acid] which results in decreased reduction of Dithionitrobenzoic Acid

[ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid

[ALB protein modified form binds to Palmitic Acid] which results in decreased reduction of Dithionitrobenzoic Acid

[ALB protein modified form binds to stearic acid] which results in decreased reduction of Dithionitrobenzoic Acid

[Pyruvaldehyde results in increased oxidation of ALB protein] which results in decreased reduction of Dithionitrobenzoic Acid

PMID:25451573
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.