GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2327
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cebpb
Name: CCAAT/enhancer binding protein beta
Acc ID: CHEBI:90705
Term: SB 203580
Definition: A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.
Chemical ID: MESH:C093642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7362086480464CTDSB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]

SB 203580 inhibits the reaction [IFNG protein results in increased phosphorylation of CEBPB protein]

PMID:16355272, PMID:24376792
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.