GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2342
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chrm1
Name: cholinergic receptor, muscarinic 1
Acc ID: CHEBI:34714
Term: dimethoate
Definition: A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.
Chemical ID: MESH:D004117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDDimethoate results in decreased expression of CHRM1 mRNA

Dimethoate results in decreased expression of CHRM1 protein

PMID:14694657, PMID:15033006
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.