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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2707
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gls
Name: glutaminase
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GLS mRNA

PMID:25607892
affects expressionISORGD:106596480464CTDAcetaminophen affects the expression of GLS mRNA

PMID:17562736
affects expressionISORGD:7366366480464CTDAcetaminophen affects the expression of GLS mRNA

PMID:25458485
increases expressionISORGD:7366366480464CTDAcetaminophen results in increased expression of GLS mRNA

PMID:21420995, PMID:25704631, PMID:26497421, PMID:26690555
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.