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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2933
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDLead results in decreased expression of ITPR1 mRNA, Lead results in decreased expression of ITPR1 protein

PMID:24960059
increases expressionEXP 6480464CTDLead results in increased expression of ITPR1 mRNA, Lead results in increased expression of ITPR1 protein

PMID:25921245
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.