Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3952
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:114816480464CTDAcetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VCAM1 protein]]

PMID:19642688
multiple interactionsISORGD:7309886480464CTDAcetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA], Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein], Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein], Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of VCAM1 protein], Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein], Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein], Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]

PMID:12615669, PMID:19281832, PMID:25876056, PMID:26901245
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.