GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3952
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:490095
Term: esculetin
Definition: A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
Chemical ID: MESH:C007628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDesculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA]

esculetin inhibits the reaction [Dietary Fats results in increased expression of VCAM1 mRNA]

PMID:28946194
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.