GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3952
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:64294
Term: 7-ketocholesterol
Definition: A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.
Chemical ID: MESH:C003001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:7309886480464CTD7-ketocholesterol results in increased expression of VCAM1 mRNA

7-ketocholesterol results in increased expression of VCAM1 protein

PMID:15720832
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.