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GENE - TERM ANNOTATION REPORT

CRRD ID: 619790
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Rag1
Name: recombination activating 1
Acc ID: DOID:8580
Term: malignant histiocytosis
Definition: Malignant neoplasms composed of MACROPHAGES or DENDRITIC CELLS. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.
Definition Source(s): MESH:D054747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

 
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:10606976, PMID:11908269, PMID:11971977, PMID:17075247, PMID:17176792, PMID:20956421, PMID:21664875, PMID:9630231
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:10701853, PMID:11133745, PMID:20489056, PMID:24290284, PMID:25516070, PMID:28492532
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:11121059
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:11121059, PMID:16276422, PMID:9630231
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:11133745, PMID:18056378, PMID:24290284, PMID:28492532
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:11313270, PMID:16276422
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:11313270, PMID:28492532, PMID:9630231
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:15908971
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:17075247, PMID:19830075, PMID:21131235, PMID:24290284, PMID:28492532, PMID:9630231
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:24033266, PMID:25741868
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:25741868
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:25741868, PMID:28492532
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:28492532
 ISORGD:13178768554872ClinVarClinVar Annotator: match by term: Histiocytic medullary reticulosis

PMID:9630231
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.