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GENE - TERM ANNOTATION REPORT

CRRD ID: 620018
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gzmb
Name: granzyme B
Acc ID: GO:0004252
Term: serine-type endopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Definition Source(s): GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IDA 2325279CRRD  
 IEAInterPro:IPR001254, InterPro:IPR001314, InterPro:IPR0181141600115InterProGO_REF:0000002

GO_REF:0000002
 ISORGD:13534951624291CRRD (PMID:11331782)

PMID:11331782
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