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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620047
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:33130
Term: aluminium hydroxide
Definition: A member of the aluminium hydroxides that has formula H3AlO3.
Chemical ID: MESH:D000536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:7333156480464CTDAluminum Hydroxide results in increased expression of IL2 mRNA

PMID:9328138
multiple interactionsISOCRRD:7333156480464CTD[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein

N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]

TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]

PMID:22075093
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.