GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620047
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:64673
Term: fumigaclavine C
Definition: An ergot alkaloid produced by the fungus Aspergillus fumigatus that is ergoline which is substituted by a 2-methylbut-3-en-2-yl group at position 2, methyl groups at the 6 and 8beta positions, and by an acetoxy group at the 9beta position.
Chemical ID: MESH:C492995
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:7333156480464CTDfumigaclavine C results in decreased expression of IL2 mRNA

fumigaclavine C results in decreased expression of IL2 protein

PMID:16023606
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.