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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620064
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chd4
Name: chromodomain helicase DNA binding protein 4
Acc ID: CHEBI:50385
Term: hemin
Definition: A heme b that has formula 651.94014.
Chemical ID: MESH:D006427
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13226846480464CTD[Hemin co-treated with hexamethylene bisacetamide] inhibits the reaction [CHD4 protein binds to OGT protein], [Hemin co-treated with hexamethylene bisacetamide] inhibits the reaction [thiamet G results in increased O-linked glycosylation of CHD4 protein], [Hemin co-treated with hexamethylene bisacetamide] results in decreased O-linked glycosylation of CHD4 protein

PMID:27231347
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.