GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620196
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: CHEBI:16336
Term: hyaluronic acid
Definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates.
Chemical ID: MESH:D006820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:15522436480464CTDHyaluronic Acid metabolite results in increased expression of MMP13 mRNA

Hyaluronic Acid metabolite results in increased expression of MMP13 protein

PMID:23692848
multiple interactionsISOCRRD:15522436480464CTD[Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP13 mRNA

PMID:23595953
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.