Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620196
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:15522436480464CTDPhenobarbital results in increased expression of MMP13 mRNA

PMID:19482888
multiple interactionsISOCRRD:15522436480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MMP13 mRNA

NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MMP13 mRNA]

PMID:19482888, PMID:24535843
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.