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CRRD ID: 620215
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Higd1a
Name: HIG1 hypoxia inducible domain family, member 1A
Acc ID: GO:0071456
Term: cellular response to hypoxia
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Definition Source(s): GOC:mah
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IEAUniProtKB:Q9JLR9, ensembl:ENSMUSP000000548811600115EnsemblGO_REF:0000107

 ISORGD:15576411624291CRRD (MGI:MGI:3654896, PMID:16815968), (MGI:MGI:5306879, PMID:21856340), (MGI:MGI:5643884, PMID:25683712)

MGI:MGI:3654896, MGI:MGI:5306879, MGI:MGI:5643884, PMID:16815968, PMID:21856340, PMID:25683712
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.