GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620267
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: S100a9
Name: S100 calcium binding protein A9
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISOCRRD:7331756480464CTDTetrachlorodibenzodioxin affects the expression of S100A9 mRNA

PMID:26377647, PMID:28922406
decreases expressionISOCRRD:7331756480464CTDTetrachlorodibenzodioxin results in decreased expression of S100A9 mRNA

PMID:28213091
increases expressionISOCRRD:13529816480464CTDTetrachlorodibenzodioxin results in increased expression of S100A9 mRNA

PMID:19619570, PMID:20106945, PMID:21835898, PMID:23152189
increases expressionISOCRRD:7331756480464CTDTetrachlorodibenzodioxin results in increased expression of S100A9 mRNA

PMID:16114106, PMID:16120747, PMID:16891777, PMID:29673856
multiple interactionsISOCRRD:13529816480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of S100A9 mRNA

PMID:19619570
multiple interactionsISOCRRD:7331756480464CTDAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of S100A9 mRNA]

PMID:16891777
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.