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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620575
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:29287
Term: gold atom
Definition: A copper group element atom that has formula Au.
Chemical ID: MESH:D006046
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7332936480464CTD[Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA, [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein

PMID:27470402, PMID:28433809
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.