GENE - TERM ANNOTATION REPORT

CRRD ID: 621017
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Acc ID: GO:0005794
Term: Golgi apparatus
Definition: A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IEAUniProtKB-SubCell:SL-01321600115UniProtGO_REF:0000039

GO_REF:0000039
 ISOCRRD:7326681624291CRRD GO_REF:0000052, PMID:15173188, PMID:20605918
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.