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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621104
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Slc22a25
Name: solute carrier family 22, member 25
Acc ID: CHEBI:17598
Term: phorbol 12,13-dibutanoate
Definition: A phorbol ester that has formula C28H40O8.
Chemical ID: MESH:D015240
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a25affects localizationISORGD:13439506480464CTDPhorbol 12, 13-Dibutyrate affects the localization of SLC22A9 protein

PMID:17341544
Slc22a25decreases activityISORGD:13439506480464CTDPhorbol 12, 13-Dibutyrate results in decreased activity of SLC22A9 protein

PMID:17341544
Slc22a25multiple interactionsISORGD:13439506480464CTDStaurosporine inhibits the reaction [Phorbol 12, 13-Dibutyrate affects the localization of SLC22A9 protein], Staurosporine inhibits the reaction [Phorbol 12, 13-Dibutyrate results in decreased activity of SLC22A9 protein]

PMID:17341544
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.