GENE - TERM ANNOTATION REPORT

CRRD ID: 621543
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: DOID:0050589
Term: inflammatory bowel disease
Definition: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
Definition Source(s): MESH:D015212, http://en.wikipedia.org/wiki/Inflammatory_bowel_disease, http://www.mayoclinic.org/diseases-conditions/inflammatory-bowel-disease/basics/definition/con-20034908
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISOCRRD:7328618554872ClinVarClinVar Annotator: match by term: Inflammatory bowel disease

PMID:10617473, PMID:11053450, PMID:11719428, PMID:11967536, PMID:12533788, PMID:14648717, PMID:14648718, PMID:14648719, PMID:15122511, PMID:15488637, PMID:15492928, PMID:15520402, PMID:16492927, PMID:16880452, PMID:17085682, PMID:18172190, PMID:19338683, PMID:19805189, PMID:21807500, PMID:21956126, PMID:22006311, PMID:22058428, PMID:22419737, PMID:22811390, PMID:22994785, PMID:23469205, PMID:24033266, PMID:24884479, PMID:25431674, PMID:25583358, PMID:25741868, PMID:26084796, PMID:26467025, PMID:26641009, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26884562, PMID:27083775, PMID:27153395, PMID:27269948, PMID:27433846, PMID:27751358, PMID:28492532, PMID:28514723, PMID:28734145, PMID:28874143
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.