GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621714
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Sptan1
Name: spectrin, alpha, non-erythrocytic 1
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases cleavageEXP 6480464CTDCalcium results in increased cleavage of SPTAN1 protein

PMID:17069801
multiple interactionsEXP 6480464CTD((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]

Edetic Acid inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]

N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]

PMID:17069801
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.