GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 628831
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDAICA ribonucleotide results in decreased expression of NR1H4 mRNA

AICA ribonucleotide results in decreased expression of NR1H4 protein

PMID:27090119
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.