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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 67378
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ncam1
Name: neural cell adhesion molecule 1
Acc ID: CHEBI:17963
Term: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Definition: A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Chemical ID: MESH:D015632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7369886480464CTD1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine results in decreased expression of NCAM1 mRNA

PMID:23933227
multiple interactionsISORGD:7369886480464CTD[Nicotine co-treated with polylactic acid-polyglycolic acid copolymer] inhibits the reaction [1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine results in decreased expression of NCAM1 mRNA], Nicotine inhibits the reaction [1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine results in decreased expression of NCAM1 mRNA]

PMID:23933227
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.