Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

CRRD ID: 68393
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Kcnd2
Name: potassium voltage-gated channel subfamily D member 2
Acc ID: GO:0043197
Term: dendritic spine
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including 'thin', 'stubby', 'mushroom', and 'branched', with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Definition Source(s): GOC:nln
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:102663, PANTHER:PTN000899042, RGD:6839313792537GO_CentralPMID:21873635

 
 IDA 1581430CRRD  
 IDA 10047325UniProtPMID:9070739

 
 ISORGD:685751624291CRRD (MGI:MGI:5299265, PMID:21943606)

MGI:MGI:5299265, PMID:21943606
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.