Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


CRRD ID: 68393
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Kcnd2
Name: potassium voltage-gated channel subfamily D member 2
Acc ID: GO:0043197
Term: dendritic spine
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including 'thin', 'stubby', 'mushroom', and 'branched', with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Definition Source(s): GOC:nln
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:102663, PANTHER:PTN000899042, RGD:6839313792537GO_CentralPMID:21873635

 IDA 1581430CRRD  
 IDA 10047325UniProtPMID:9070739

 ISORGD:685751624291CRRD (MGI:MGI:5299265, PMID:21943606)

MGI:MGI:5299265, PMID:21943606
Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.