GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69313
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:16348
Term: 3-nitropropanoic acid
Definition: A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Chemical ID: MESH:C015392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTD3-nitropropionic acid results in increased activity of ACHE protein

PMID:25445565, PMID:27206696
multiple interactionsEXP 6480464CTDthymoquinone inhibits the reaction [3-nitropropionic acid results in increased activity of ACHE protein]

trandolapril inhibits the reaction [3-nitropropionic acid results in increased activity of ACHE protein]

PMID:25445565, PMID:27206696
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.