GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69313
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:28794
Term: coumarin
Definition: A chromenone having the keto group located at the 2-position.
Chemical ID: MESH:C030123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7358796480464CTDcoumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]

coumarin inhibits the reaction [haloxon results in increased phosphorylation of ACHE protein]

coumarin inhibits the reaction [Paraoxon results in increased phosphorylation of ACHE protein]

PMID:10421444
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.