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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69313
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:8776
Term: ranitidine
Definition: A member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease.
Chemical ID: MESH:D011899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDRanitidine affects the reaction [Paraoxon results in decreased activity of ACHE protein]

PMID:15669039
multiple interactionsISORGD:7358786480464CTDRanitidine binds to and results in decreased activity of ACHE protein, Ranitidine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]

PMID:15669026, PMID:16193528
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.