GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69651
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor 2
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDThioacetamide results in decreased expression of TGFBR2 mRNA

PMID:17621560
increases expressionEXP 6480464CTDThioacetamide results in increased expression of TGFBR2 mRNA

PMID:28181416
multiple interactionsEXP 6480464CTD[Thioacetamide co-treated with Lipopolysaccharides] results in decreased expression of TGFBR2 mRNA

[Thioacetamide co-treated with Lipopolysaccharides] results in decreased expression of TGFBR2 protein

PMID:17621560
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.