GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 70069
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cxcl2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:33101
Term: nitrogen dioxide
Definition: A nitrogen oxide that has formula NO2.
Chemical ID: MESH:D009585
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Ozone co-treated with Nitrogen Dioxide] results in increased expression of CXCL2 mRNA

PMID:10986008
increases expressionISOCRRD:7331186480464CTDNitrogen Dioxide results in increased expression of CXCL2 mRNA

Nitrogen Dioxide results in increased expression of CXCL2 protein

PMID:10715624, PMID:11498801
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.