GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | multiple interactions | EXP | | 6480464 | CTD | Sirolimus inhibits the reaction [HRAS protein mutant form results in increased expression of MIR146A mRNA], Sirolimus inhibits the reaction [HRAS protein mutant form results in increased expression of MIR193A-1 mRNA], Sirolimus inhibits the reaction [HRAS protein mutant form results in increased expression of MIR21-1 mRNA], Sirolimus inhibits the reaction [HRAS protein mutant form results in increased expression of MIR21-2 mRNA], Sirolimus inhibits the reaction [HRAS protein mutant form results in increased phosphorylation of RPS6 protein] | PMID:30619488 | multiple interactions | ISO | RGD:10730 | 6480464 | CTD | [Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein, [Sirolimus co-treated with HRAS protein] results in decreased expression of HSPA5 protein, PPARD protein affects the reaction [[Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein], PPARD protein affects the reaction [[Sirolimus co-treated with HRAS protein] results in decreased expression of HSPA5 protein] | PMID:24898257 | | ||||||||||||||||||||||
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