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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730927
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL5
Name: interleukin 5
Acc ID: CHEBI:81501
Term: 1,2,3,7,8-Pentachlorodibenzodioxin
Definition: A dibenzodioxine that has formula C12H3Cl5O2.
Chemical ID: MESH:C051452
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:107996480464CTD1, 2, 3, 7, 8-pentachlorodibenzo-p-dioxin analog results in decreased expression of IL5 protein, 1, 2, 3, 7, 8-pentachlorodibenzo-p-dioxin results in decreased expression of IL5 protein

PMID:19041680
increases expressionISORGD:107996480464CTD1, 2, 3, 7, 8-pentachlorodibenzo-p-dioxin analog results in increased expression of IL5 mRNA

PMID:19041680
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.