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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730959
Species: Homo sapiens
CRRD Object: Gene
Symbol: SLC9A2
Name: solute carrier family 9 member A2
Acc ID: CHEBI:26708
Term: sodium atom
Definition: An alkali metal atom that has formula Na.
Chemical ID: MESH:D012964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases uptakeISORGD:37196480464CTDSLC9A2 protein results in increased uptake of Sodium

PMID:10958346
multiple interactionsISORGD:37196480464CTD[Amiloride results in decreased activity of SLC9A2 protein] which results in decreased transport of Sodium, [cariporide results in decreased activity of SLC9A2 protein] which results in decreased transport of Sodium, Ammonia inhibits the reaction [SLC9A2 protein results in increased uptake of Sodium]

PMID:10958346
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.